IDENTIFICATION OF FIBROBLAST GROWTH FACTOR RECEPTOR 3 (FGFR3) AS A PROTEIN RECEPTOR FOR BOTULINUM NEUROTOXIN SEROTYPE A (BONT/A).

Identification of fibroblast growth factor receptor 3 (FGFR3) as a protein receptor for botulinum neurotoxin serotype A (BoNT/A).

Botulinum neurotoxin serotype A (BoNT/A) causes transient muscle paralysis by entering LPs motor nerve terminals (MNTs) where it cleaves the SNARE protein Synaptosomal-associated protein 25 (SNAP25206) to yield SNAP25197.Cleavage of SNAP25 results in blockage of synaptic vesicle fusion and inhibition of the release of acetylcholine.The specific upt

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Optimal Micro-Siting of Weathervaning Floating Wind Turbines

This paper presents a novel tool for optimizing floating offshore wind farms based on weathervaning turbines.This solution is grounded on the ability of the assembly (wind turbine plus floater) to Weight Control self-orientate into the wind direction, as this concept is allowed to freely pivot on a single point.This is a passive yaw potential solut

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Bubble formation in shear-thinning fluids: Laser image measurement and a novel correlation for detached volume

A laser image system has been established to quantify the characteristics of growing bubbles in quiescent shear-thinning fluids.Bubble formation mechanism was investigated by comparing the evolutions of bubble instantaneous shape, volume and surface area in GLUCOMANNAN two shear-thinning liquids with those in Newtonian liquid.The effects of solutio

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